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setuptools 50.0 MSVC: CCompiler_spawn() got an unexpected keyword argument 'env'

After upgrading to setuptools 50.0, my Cython-based package extensions no longer build. The 'env' in return super().spawn(cmd, env=env) seems to be the problem. self.run_command('build_ext') File ...
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No module named 'numpy.distutils._msvccompiler' in numpy.distutils; trying from distutils error: Microsoft Visual C++ 14.0 or greater is required.

Downloading six-1.12.0-py2.py3-none-any.whl (10 kB) Collecting scipy==1.3.1 Ignoring numpy: markers 'python_version == "3.5" and platform_system != "AIX"' don't match your environment Ignoring numpy: ...